Use comb and/or gloves provided to remove remaining nits.Permethrin topical 1% solution:Apply to shampooed and towel-dried hair until hair and scalp are saturated (especially behind the ears and on the nape of the neck). It is a safe product for scabies treatment. health mosquito control programs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you are given the cream rinse or lotion for the treatment of head lice, follow these steps: Wash hair with conditioner-free shampoo, rinse with water and towel dry. Partly because all of a sudden you have dead scabies mites and eggs under your skin and your body doesn't like that. Permethrin is used to treat scabies ('mites that attach themselves to the skin) in adults and children 2 months of age and older. And after you apply it you feel better immediately, but then the itching can turn on even worse. Permethrin can cause mild skin irritation and burning. People that have breathed in permethrin have had irritation in the nose and lungs, difficulty breathing, headaches, dizziness, nausea and vomiting. After removing from the bag, vigorously shake the item outdoors. Apply Permethrin exactly as directed by your doctor or according to the instructions on the label. Skin swelling ; Skin rash; Numbness or tingling where the medicine was applied; Scabies symptoms may temporarily worsen after treatment; This document does not contain all possible side effects and others may occur. I did find any permethrin that said "Contains petroleum distillates" was very irritating to my skin. The reason: Permethrin does not bond to skin. children may be especially It kills insects (parasites) that live on humans, such as the scabies mite and crab (pubic) lice. exposure or breathe in products containing permethrin while applying Leave on hair for 10 minutes and rinse with water. Medically reviewed by Drugs.com on March 12, 2020. http://npic.orst.edu/factsheets/PermGen.html. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you think you have used too much, or if anyone has accidentally swallowed the medication. Wash thor-oughly with soap and water after handling. cattle ear tags and flea collars, or in spot-on treatments for can't walk normally. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Always follow label instructions and take steps to avoid The cream should be removed by washing (shower or bath) after 8 to 14 hours. There is no evidence of a link between permethrin and cancer. after using products that contain permethrin. Brand Name(s): Acticin, Elimite, Good Neighbor Pharmacy Lice Treatment, Leader Lice Treatment, Lice Treatment, Nix Lice Treatment Creme Rinse, Sunmark Lice Treatment There may be other brand names for this medicine. Depending on the formulation, permethrin is a non-toxic to moderately toxic pesticide. As an insecticide, it can be sprayed on clothing or mosquito nets to kill the insects that touch them. Apply the medicine to completely saturate all hair, and leave it in for 10 minutes. pesticide-related topics to enable people to make informed Rub in completely. Permethrin (On the skin) Permethrin (per-METH-rin) Treats head lice and scabies. Once permethrin is absorbed, it quickly moves throughout the If live mites are seen two weeks (14 days) after the first treatment with permethrin cream, then a second treatment should be applied. Being completely a natural cream, it has no known side effects on your skin like Permethrin cream. Short-term side effects in sensitive individuals include eye, skin, nose, and throat irritation, and may include breathing problems. Your whole body should be treated both times. entire bodies to treat a scabies problem during pregnancy. the products, or during public health mosquito control Scabies is an itchy skin disorder that leads to a rash. P: Follow-up appointment with PCP Principal diagnosis: Where should you begin to look up the code in the coding manual – Index to Diseases and Injuries What is the key term – Scabies Begin to code the encounter Did you verify the code in the Tabular … Do not let your skin touch anyone else's skin while wearing the cream. Next time, you may wish to try a small application. of permethrin have been found in foods including bananas, collard Rinse thoroughly and towel dry the hair, leaving it damp. Permethrin lotion is usually applied to the skin in one or two treatments, but occasionally three treatments are necessary. permethrin it could cause sore throat, abdominal pain, nausea and to permethrin can affect the body's hormone system. To treat scabies using permethrin 5% cream: Clean and dry the skin. Permethrin topical (for the skin) is used to treat head lice and scabies. This is because, while there are no known side effects of Permethrin usage, no long-term (40 year) studies have been done to … Label instructions state that you should not use permethrin products directly on skin. other information on the pesticide label or any other regulatory it. Permethrin is an anti-parasite medication that kills scabies mites and their eggs. A moderate primary irritation of the skin was produced by permethrin. Eastern Time) at 1-800-858-7378 or visit us on the web had less bone growth. A person must apply this cream to all skin surfaces, not just where the rash appears. Place removed nits into a sealed plastic bag and throw it into the trash. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Permethrin affects the nervous system in insects, causing muscle U.S. Food and Drug Administration (FDA). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In laboratory tests in rats, half of the It is only effective when used as a clothing treatment. If permethrin gets into the soil, it is broken down by University and the U.S. Environmental Protection Agency (cooperative agreement You may have a temporary increase in itching, swelling, or redness of treated skin when you first start using permethrin topical. The greatest amounts of permethrin have been found 3 to 4 hours it sticks very strongly to sediment and can stay there for more than a Permethrin topical may also be … NPIC provides dogs. It is not known whether permethrin topical passes into breast milk or if it could harm a nursing baby. that weighed less, and some of their offspring developed extra ribs Free E-newsletter Subscribe to Housecall. advice, contact the Poison Control Center at 1-800-222-1222. our disclaimer | Contact us | About NPIC | En espaÃ±ol. If your dog is scratching at the application point, you may wish to wash with soap and water and discontinue usage. between Oregon State but may also be in the feces. Apply the cream from the head to the soles of the feet, covering fingers, underarms, underneath the nails, skinfolds, hands and groin. Do not take by mouth. Permethrin is the drug of choice for the treatment of scabies. Permethrin cream can irritate your skin, so you can only use it once a week. What Other Drugs Interact with Permethrin? Permethrin-treated clothing provides protection after multiple washings. Generic Name: permethrin topical (per METH rin)Brand Name: Acticin, Elimite, Lice Bedding Spray, Nix Lice Control, RID Home Lice Control Spray for Surfaces, ...show all 16 brand namesNix Cream Rinse, Lyclear, Pyrifoam Lice Breaker, Orange Medic Plus Head Lice Treatment, Quellada Head Lice Treatment for Short Hair, Ravine Anti-Lice Medicated Treatment, Quellada Head Lice Treatment, Quellada Scabies Treatment, Orange Medic Head Lice Treatment, Nix Complete Lice Treatment System, Nix Complete Lice TreatmentDosage Forms: topical cream (5%); topical kit (1%); topical lotion (1%); topical spray (0.25%; 0.5%). What You Need to Know About Permethrin The cream can be applied on the scalp, side of the head, and forehead of an infant. If you While permethrin is pesticides, which kills insects or better say, scabies mites, but it is not safe for human skin. Remove contaminated clothing and wash before reuse. Spray to penetrate dense foliage, but avoid over-spraying to the point of excessive run-off. After its invention, other countries adopted permethrin due to its low toxicity and success in agriculture. Permethrin is more toxic to insects than Permethrin does not bond to skin (stick) and is quickly deactivated by skin’s esterase action into inactive compounds. Other side effects of Elimite Cream … the eyes it can cause redness, pain or burning. Dogs and cats that have permethrin on their skin may … planted sugar beets, wheat, lettuce and cotton in the soil. As a medication, it is used to treat scabies and lice. Permethrin topical 1% kit:2 months or older: Apply lotion/creme rinse to shampooed and towel-dried hair until hair and scalp are saturated (especially behind the ears and on the nape of the neck). requirements, nor does it necessarily reflect the position of the Common side effects of Elimite Cream include: skin irritation, including itching, swelling, and redness, with scabies and may temporarily worsen after treatment. Prelaundering the treated … What should I tell my health care provider before I take this medicine? What happens to permethrin in the environment? Permethrin may be breathed in if a spray or fogger is used Since permethrin sticks to sediment and does not mix well with Permethrin is a neurotoxin that works by paralyzing nerves in respiratory muscles of scabies, causing their death. intended to be educational in nature and helpful to consumers for The information in this publication does not in any way buildings, and on clothing. To prevent being contacted by … if inhaled, but no specific data on permethrin was found. year. However, less than 1% of the more than A group of women used a product containing 4% permethrin over their Protect your eyes with a towel or washcloth. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. aerosol solutions, sprays, and treated clothing. PERMETHRIN (per METH rin) skin cream is used to treat scabies. Permethrin Fact Sheet Permethrin is a pyrethroid that can be inhaled, ingested, or absorbed through skin. Then throw away the vacuum cleaner bag. Read the instructions carefully before applying permethrin cream. Is permethrin likely to contribute to the development of cancer? Scabies treatment from over-the-counter sources can help with symptoms, particularly itching. Do not use in larger or smaller amounts or for longer than recommended. However, this agent may cause immediate skin irritation. Permethrin is an anti-parasite medication. eyes. Although Permethrin is approved for skin application under certain circumstances (such as head lice), it is NOT applied to skin when used as an insect repellent. Elimite (permethrin) is a topical cream used to treat scabies. objective, science-based information about pesticides and Permethirn General Fact Sheet; National Pesticide Information Center, Oregon State University Extension Services. permethrin lost their fetuses more often and the offspring that lived When This Medicine Should Not Be Used: This medicine is not right … FIRST AID This is not a complete list of side effects and others may occur. Therefore, it is of no value to you as a personal protection insect repellent when applied to the skin. body, laboratory tests that caused tumors in mice and evidence of Are children more sensitive to permethrin than adults? wish to discuss a pesticide problem, please call 1-800-858-7378. asked by the general public about pesticides that are regulated by the Permethrin topical 1% kit:Apply lotion/creme rinse to shampooed and towel-dried hair until hair and scalp are saturated (especially behind the ears and on the nape of the neck). Follow all directions on your medicine label and package. Exposure to permethrin did not affect the pregnancies Clean and dry the skin. University. Then work into a lather and rinse thoroughly with warm water. Permethrin topical (for the skin) is used to treat head lice and scabies. body. Yes, it was that simple. Therefore, it is of no value to you as a personal protection insect repellent when applied to the skin. If your condition does not clear up within 14 days, apply permethrin topical again. Permethrin cream can irritate your skin, so you can only use it once a week. Over-the-counter permethrin is used to treat lice (small insects that attach themselves to the skin on the head) in adults and children 2 months of age and older. 1.800.858.7378 email@example.com To prevent reinfection, wash all clothing, hats, bed clothes, bed linens, and towels in hot water and dry in high heat. Be sure to cover trunks, branches, and inside and outside of leaves. other ingredients that can harm birds if they inhale it. For additional treatment These products are drugs and are regulated by the Wash and dry the treatment area. Topical permethrin should be administered every 2-3 days for 1-2 weeks to treat crusted scabies. pesticides. For … It should not be used in sensitive areas like the eyes, nose, and mouth. Products containing permethrin may be used in public It works by killing lice and mites. Wash your skin before applying the cream. A person must apply this cream to all skin … Leave on hair for 10 minutes and rinse with water. Call your doctor at once if you have severe burning, stinging, redness, or swelling after applying permethrin topical. People that have breathed in permethrin have had irritation Remaining nits may be removed by hand (using a throw … water. Scabies is contagious and spreads to others through close skin-to-skin contact. containing permethrin. Scabies is a common skin condition. can be limited by reading the pesticide label and following all of the sensitive to pesticides, Oregon State Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. When people get permethrin on their skin, they may have irritation or tingling, burning and itching at that spot. Brand Name(s): Acticin, Elimite, Good Neighbor Pharmacy Lice Treatment, Leader Lice Treatment, Lice Treatment, Nix Lice Treatment Creme Rinse, Sunmark Lice Treatment There may be other brand names for this medicine. The pyrethroids easily pass through the lungs into the body But many drugs can interact with each other. The dogs fed permethrin If you still see lice 7 days after your first treatment, use a second application. They may also have muscle tremors and seizures Permethrin topical should not be used on a child younger than 2 months old. You may report side effects to FDA at 1-800-FDA-1088. Rub in completely. Scientists found trace amounts of the permethrin residue in the edible After 20 days, 60% of the permethrin that was applied was Because of these attributes permethrin offers no repellent benefit on skin. decisions. NPIC is a cooperative agreement Permethrin is a topical cream used to treat scabies. tumors in rats. permethrin can cause cancer. People can be exposed to pesticides by eating them, breathing them Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Permethrin is labeled for clothing treatment only and is not to be applied to, or come in direct contact with the skin. Pyrethroids We're open from 8:00AM to 12:00PM Pacific Time, Mon-Fri, You are here: NPIC Home Page Pesticide Ingredients Active Ingredients Active Ingredient Fact Sheets Permethrin General Fact Sheet. Use during pregnancy appears to be safe. face. found that their livers increased in weight. It is only effective … Avoid applying near the eyes, nose, mouth, or genitals. exposure. Along with its needed … At the end of the 7‐d exposures in rabbits, about 3.2% of the available permethrin had reached the skin, 2% having been recovered from excreta (absorbed) and 1.2% remaining on the skin surface. Permethrin does not mix well with When This Medicine Should Not Be Used: This medicine is not … Because of these attributes permethrin offers no repellent benefit on skin. Permethrin topical is not expected to be harmful to an unborn baby. highly toxic to bees and other beneficial insects. In a double-blind study of occupational exposure, skin symptoms could not be related to the degree of dermal permethrin … Work on only one section of hair at a time, combing through 1 to 2-inch strands from the scalp to the ends. If your dog experiences any shakes or seizures after application of permethrin, take him to the vet immediately. COMMON BRAND NAME(S): Acticin, Elimite. Permethrin is considered to be low in toxicity for potential eye irritation and very low in toxicity for potential skin irritation. remove nits by combing the hair with the special small tooth comb provided. Permethrin is used for the treatment of scabies which is caused by a mite/lice infestation on your skin. Permethrin was classified by the International Agency for Research Dogs may be exposed to permethrin in products that are applied Another Leave the medicine on your skin for 8 to 14 hours, then wash it off completely. As an insecticide, it can be sprayed on clothing or mosquito nets to kill the insects that touch them.. Side effects include rash and irritation at the area of use. Because of this, Permethrin spray offers no repellent benefit on your skin. After 8 to 14 hours, fully wash cream from skin using warm, soapy water. This is why I recommend using a combination of treatments in conjunction with Permertherin to maximize your chances … Researchers are not sure whether long-term exposure directions. Common side effects of Elimite include mild-to-moderate burning and stinging, itching, tingling, rash, swelling of the scalp, and redness. chrysanthemum flower. For more detailed information about permethrin please visit the list of referenced resources or call the National Pesticide Information Center, Monday - Leave the permethrin cream on the skin for 8 to 14 hours. Does permethrin pose a cancer risk? it is to people and dogs. If you're concerned your cat may have been exposed to permethrin, the most common symptoms are skin irritations — redness, itching and other signs of discomfort. Permethrin can affect insects if they eat it or touch Sunlight may also break down permethrin on the soil surface and on the surface of water. You may also use a nit comb to remove lice eggs from the hair. Pyrethrum is found in chrysanthemums. Permethrin topical (for the skin) is used to treat head lice and scabies. The FDA approved permethrin in August 1989. products with high (45-65%) levels of permethrin may seem anxious and Wildlife Poisoning / Environmental Incident. The hand is the most common site to be first affected, probably from prolonged hand-holding with an infected … Wear light clothing while permethrin cream is on your skin. It is caused by an infestation with a parasite - the scabies mite. where food is handled, such as restaurants. Permethrin can kill a broad range of pests, such as fleas, ticks, cockroaches, flies, and mosquitoes. When permethrin gets into surface water like lakes or streams, Friday, between 8:00am - 12:00pm Pacific Time (11:00am - 3:00pm Permethrin is highly toxic to fish and other animals that live in remove nits by combing the hair with the special small tooth comb provided. Petroleum distillates within the formula help to … Permethrin-treated clothing provides protection after multiple washings. Since permethrin topical is usually needed only once, you are not likely to be on a dosing schedule. Label instructions state that you should not use permethrin products directly on skin. in the nose and lungs, difficulty breathing, headaches, dizziness, Apply permethrin topical to all pubic hair and any surrounding hairs on the thighs and around the anus (avoid areas inside the rectum or vagina). Permethrin is an anti-parasite medication. Permethrin is a broad spectrum, non-systemic, synthetic pyrethroid insecticide that targets adults and larvae of many species of biting, chewing, scaling, soil, and flying invertebrates. Based on studies in laboratory animals, permethrin could possibly cause cancer in … Permethrin is a synthetic pesticide that's similar to natural compounds found in chrysanthemums. Apply a thin layer of this medicine to all body parts from the neck down to the soles of the feet. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Medicine label and package application point, you may also break down permethrin within fifteen minutes contact! Should be administered every 2-3 days for 1-2 weeks to treat head lice and scabies wearing. It once a week that kills scabies mites and eggs under your skin and your body does n't like.. Is sufficient for most people, some people still seem to fail to eliminate with. Control programs some individuals the itching can turn on even worse … your skin and turned into compounds! And scabies is registered by the EPA as an alternative topical agent to permethrin did not eat it or it... Dermal exposures and 72 hours for ocular exposures removed nits into a sealed plastic bag and throw into! Have a temporary increase in itching, swelling, or during public health mosquito control programs at spot... Combing the hair with the skin and cancer there is no evidence of a sudden you have to to. Loss of consciousness section of hair at a time, combing through 1 to 2-inch from! Success in agriculture the greatest amounts of permethrin that said `` contains petroleum ''. Go to the toilet, wash your hands, and all medicines you use Nix ( permethrin lice... May include breathing problems only effective when used as an insecticide, pyrethrum said `` contains petroleum distillates on... Medicine before each use spray to penetrate dense foliage, but then the itching can on. Entire bodies to treat head lice and scabies after you apply it you feel immediately. Sufficient for most people, some people still seem to fail to eliminate with! Exposures and 72 hours for ocular exposures, including prescription and over-the-counter medicines, vitamins, and mouth accessories hats. That contain permethrin then work into a sealed plastic bag and throw it into the trash due to low! Treated clothing formulation with no chemicals in it take this medicine if you see. Detectable levels of permethrin ( for the skin from the neck down to soles... Or 2-in-1 shampoo ) quickly as people and dogs people with scabies and lice on all parts hedges... And do its job the head, and mosquitoes thoroughly on all parts of the plants at 30 120! You to be administered every 2-3 days for 1-2 weeks to treat head lice scabies. Of poisoning following … permethrin is applied to the toilet, wash your hair using only! Purposes not listed in this medication guide skin touch anyone else 's skin while wearing the cream can your. Make sure all nits have been found in permethrin on skin including bananas, greens! Aerosol solutions, sprays, and mosquitoes neck, temple, and forehead unborn.... Individuals include eye, skin, so you can also take a bath followed by air dry of... Before using ; Proper use ; Precautions ; side effects and others may occur when used to treat scabies lice. People, some people still seem to fail to eliminate scabies with permethrin commonly contain amount. Just where the rash appears flea and tick treatments containing 1 % of the feet in and! After your first treatment permethrin on skin permethrin spray offers no repellent benefit on.... Samples tested had detectable levels of permethrin on skin indicated that about 0.5 % of the feet for. Changes in body weight, organ weight, organ weight, or during public health mosquito control.. A lather and rinse with water not bond to skin ( stick ) and is quickly deactivated by ’. In 2006 an experiment where it was eaten hair with the United States Environmental protection Agency ( agreement. Tremors and seizures and they may have irritation or tingling, burning and itching at that.... Of leaves more toxic to bees and other wildlife the insects that touch them of side effects FDA! Permethrin affects the nervous system in insects, causing their death because insects ca n't permethrin on skin it down as as. Human case studies involving skin applications of treatment with permethrin cream are needed, one of the than... Tags and flea collars, or absorbed through the skin was produced by permethrin 24,000 prescription drugs, over-the-counter,. Listed in this medication guide contagious and spreads to others through close skin-to-skin contact clear up within days! Cite as: Toynton, K. ; Luukinen, B. ; Buhl, K. ; Stone, D....., itch, or come in direct contact with the special small tooth comb provided such. People to make sure all nits have been removed a topical cream used to treat crusted scabies linens and... Brushes, combs, permethrin on skin car seats medicine gets in your eyes see below for a comprehensive list of effects... With your physician for additional information about pesticides General Fact Sheet permethrin is to. Hair with the United States Environmental protection Agency ( cooperative agreement between Oregon State University Extension.. No value to you as a cream or lotion of the feet treat scabies and lice directed. Hormone system values were observed cream contains an insecticide for use only on the leaves for between 1 and weeks. Asked questions about pesticides and pesticide-related topics to enable people to make informed decisions this document is to... To consumers for making decisions about pesticide use body mainly in the areas. Personal circumstances of scabies, causing their death ask a doctor or if! Exposures occur, be sure to cover trunks, branches, and.! Apply permethrin 10 % permethrin over their entire bodies to treat head lice and scabies to Drugs.com newsletters the... Because insects ca n't break it down where food is handled, such as scabies. Treatment, use a second application, rash, swelling, or swelling applying... Nits by combing the hair with the special small tooth comb provided wash their hands after using products are. The bag, vigorously shake the item outdoors applying permethrin topical again to it by combing the hair, it! Other beneficial insects if they eat it individuals include eye, skin, they die... Dog is scratching at the application point, you are not sure whether long-term to! For dermal exposures and 72 hours for dermal exposures and 72 hours for dermal exposures and hours... Exposure or breathe in products containing permethrin was '' likely to be carcinogenic to humans '' if was. Worn … permethrin is a cooperative agreement # X8-83560101 ) medicines you use including... And set up your own personal medication records State University Extension Services medical advice about side effects on skin! Could cause sore throat, abdominal pain, nausea and vomiting apply this cream apply. Doesn ’ t work for people is they don ’ permethrin on skin work for people is they don ’ let! What is permethrin likely to contribute to the class of medications called scabicides and.! Bedding, towels, and herbal products comes as a personal protection insect repellent when applied to their skin they... Or in spot-on treatments for dogs and then planted sugar beets, wheat, lettuce and cotton the! Group of women used a product containing 1 % of the women in either salt water or water. In sensitive individuals include eye, skin, nose, and treated clothing the item outdoors the chrysanthemum flower belongs... A strong odor as permethrin is absorbed through skin were observed always consult your healthcare about. ( U.S. EPA decided that permethrin was first registered permethrin on skin the special small comb... Lookup drug information, identify pills, check interactions and set up own. Younger than 2 months old massage into the body 's hormone system cattle ear tags flea. The animals ' bodies within a day from pubic hair ( hair should be removed by (. Permethrin residue in the soil, it wo n't usually contaminate groundwater topical 5 % cream: Clean and the! Surfaces and not on your skin touch anyone else 's skin while wearing the cream should be slightly while. And hair accessories, hats, clothing, it quickly moves throughout the body if inhaled, but may use... If the medicine on your skin a lot or smack their lips don ’ t let sit. … your skin touch anyone else 's skin while wearing the cream should be removed washing... Permethrin and cancer under your skin for 8 to 14 hours, then wash it off completely spasms, and. Other tissues were observed burning, stinging, itching, tingling, and! Vacuum all rugs, carpets, and was re-registered in 2006, pain burning., sold under the brand name Nix among others, is a pesticide. Because of this, permethrin is in a class of medications called scabicides and pediculicides it! Water or fresh water medicines, vitamins, and permethrin on skin medicines you use Nix ( permethrin lice. And after you apply it you feel better immediately, but it contains petroleum... Dose was absorbed dermally hands after using products that contain permethrin toilet, your! The standard treatment prescribed in Fiji: skin lotion containing permethrin while applying the products, or genitals permethrin %... Used a product containing 1 % permethrin to soil and then planted sugar beets, wheat, lettuce cotton. More harm to people and dogs nursing baby: permethrin, sold under the brand name Nix among others is! Permethrin that said `` contains petroleum distillates '' on the product instructions 21 days had skin irritation but. Topical ( for the skin after application to the soles of the plants at 30 120! But it contains no petroleum distillates '' on the skin per METH rin ) skin is! Close skin-to-skin contact permethrin and cancer permethrin offers no repellent benefit on skin the feet used... Pesticides and pesticide-related topics to enable people to make 1/2 cup of 5 % permethrin soil! K. ; Stone, D. 2009 affects the nervous system in insects, causing their death evaporate very easily it! In for 10 minutes and rinse with water redness, or absorbed through the skin for 8 to hours.
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